Finally, vitamin B12 levels were measured in vitamin D_{step step 3} deficient and vitamin D₃ normal group, and then these two groups were divided into subgroups of their own.

Primary endpoints are as follows: (1) determining the 25-(OH) D₃ level in the general population and in patients with CKD; (2) comparing the clinical and laboratory data regarding inflammation with levels of 25-(OH) D₃; (3) evaluation of whether low and normal 25-(OH) D₃ levels and inflammation could explain this potential association;

dos.2. Biochemical Study

25-Hydroxyvitamin D₃ levels were measured by high performance liquid chromatographic analysis performed with using a Zivak HPLC system (Gebze, Turkey) using a commercial 25-OH vitamin D₃ kit (Recipe, Munich, Germany). The reference values were 10–50 ?g/L for winter, 20–120 ?g/L for summer seasons. A deficiency in 25-(OH) D₃ level was considered as below 10 ?g/L.

Gel vitamin B12 and plasma PTH account was indeed measured that have chemiluminescence approach by Immulite 2000 (Diagnostic Affairs Corp., Los angeles, USA).

2.step three. Mathematical Investigation

Mathematical analyses was basically did of the SPSS 18.0 software (SPSS Inc., Chi town, IL, USA). Shipping of data try determined by Kolmogorov-Smirnov try. Continued details was in fact shown as the median (minimum-maximum) and you can categorical details once the regularity and you can percent. Carried on variables was basically compared to the newest Mann-Whitney

make sure categorical details was basically opposed playing with Pearson’s Chi-square sample. Linear relation ranging from a couple carried on details are analyzed by Spearman correlation analysis.

3. Overall performance

A total of 1897 subjects were included in this retrospective study. Patients that measured 25-(OH) D₃ levels under 10 ?g/l were 598 (31.5%), the number of those between 10 and 21 ?g/L was 751 (39.5%), and the number of those over 21 ?g/L was 550 (28.9%), respectively, in the study group (Figure 1).

(3–121)] compared to men [ (3–201)]. For this reason, male and female people was basically put into teams with respect to the visibility off kidney inability. The results is described into the Dining tables 3 and you can cuatro.

There was no significant correlation between age and vitamin D₃ deficiency in our study population. There were lower serum albumin levels in patients with vitamin D₃ deficiency, but this was not statistically significant (Table 3). Median serum creatinine levels were less in patients with vitamin D₃ deficiency without renal failure than in participants with normal vitamin D₃ levels without renal failure (Table 4).

₃ deficiency and vitamin D₃ normal in male and female patients without renal failure (Tables 1–4). There was no difference in the levels of albumin, CRP, ESR, and WBC in women with renal insufficiency, but there was significant difference between levels of serum albumin and ESR in male patients.

In CRP variable that was categorized as <6 mg/L and ?6 mg/L, there was no significant difference between CRP categories and 25-(OH) D₃ levels ( ). The results are summarized in Table 5.

In CRP variable that was categorized as <6 mg/L and ?30 mg/L, there was no significant difference between these CRP categories and 25-(OH) D₃ levels (

Then, all participants were included in the study, both 25-(OH) D₃ and CRP variables taken as a numerical, and correlation analysis was performed. There was no correlation between the two groups (

CRP and vitamin Dating einen jüngeren Mann in Ihren 40-er D₃ levels in men and women were different; therefore, similar analyses were repeated in men and women groups. Median CRP in vitamin D₃ deficient group and vitamin D₃ normal group showed no significant difference in the male and female patients.

When 25-(OH) D₃ and CRP variables are taken as categorical variables and analyzing the relationships between variables, no significant correlation was found ( ).